› 2mbk

Solution NMR

The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed

Released:
DOI: 10.2210/pdb2mbk/pdb
PDB entry 2mbk coloured by chain, ensemble of 10 models, front view.
PDB entry 2mbk coloured by chain, ensemble of 10 models, side view.
PDB entry 2mbk coloured by chain, ensemble of 10 models, top view.
Source organism: Danio rerio
Primary publication:
The clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed.
Fiebig JE, Weidauer SE, Qiu LY, Bauer M, Schmieder P, Beerbaum M, Zhang JL, Oschkinat H, Sebald W, Mueller TD
Molecules 18 11658-82 (2013)
PMID: 24071977

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176965 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Crossveinless 2 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 7.34 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5D734 (Residues: 28-93; Coverage: 10%)
Gene names: bmper, cvl2, id:ibd5071
Structure domains: Defensin A-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

BMP signalling: agony and antagony in the family.
Brazil et al. (2015)
2 more

2 mentions without citation

Structural Biology and Evolution of the TGF-β Family.
Hinck et al. (2016)
1 more