› 2lbw

Solution NMR

Solution structure of the S. cerevisiae H/ACA RNP protein Nhp2p-S82W mutant

Released:
DOI: 10.2210/pdb2lbw/pdb
PDB entry 2lbw coloured by chain, ensemble of 20 models, front view.
PDB entry 2lbw coloured by chain, ensemble of 20 models, side view.
PDB entry 2lbw coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.
Koo BK, Park CJ, Fernandez CF, Chim N, Ding Y, Chanfreau G, Feigon J
J Mol Biol 411 927-42 (2011)
PMID: 21708174

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152329 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
H/ACA ribonucleoprotein complex subunit NHP2 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.31 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32495 (Residues: 36-156; Coverage: 78%)
Gene names: D1045, NHP2, YDL208W
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Structure domains: 60s Ribosomal Protein L30; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 70%
Refinement method: simulated annealing
Expression system: Saccharomyces cerevisiae

Quick links

Citations

7 review citations

Small nucleolar RNAs and RNA-guided post-transcriptional modification.
Lui et al. (2013)
6 more

3 mentions without citation

Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.
Koo et al. (2011)
2 more