Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127258 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP-dependent protein kinase inhibitor alpha
Molecule details ›
Chain: A
Length: 27 amino acids
Theoretical weight: 2.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: cAMP-dependent protein kinase inhibitor
Length: 27 amino acids
Theoretical weight: 2.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61925 (Residues: 30-54; Coverage: 33%)
Sequence domains: cAMP-dependent protein kinase inhibitor
Exportin-1
Molecule details ›
Chain: B
Length: 127 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: CRM1 / Exportin repeat 3
Structure domains: de novo design (two linked rop proteins)
Length: 127 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O14980 (Residues: 504-630; Coverage: 12%)
Sequence domains: CRM1 / Exportin repeat 3
Structure domains: de novo design (two linked rop proteins)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression system: Escherichia coli
