› 2ke4

Solution NMR

The NMR structure of the TC10 and Cdc42 interacting domain of CIP4

Released:
DOI: 10.2210/pdb2ke4/pdb
PDB entry 2ke4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ke4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ke4 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The NMR structure of the TC10- and Cdc42-interacting domain of CIP4.
Kobashigawa Y, Kumeta H, Kanoh D, Inagaki F
J Biomol NMR 44 113-8 (2009)
PMID: 19387844

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172357 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cdc42-interacting protein 4 Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 11.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15642 (Residues: 388-481; Coverage: 16%)
Gene names: CIP4, STOT, STP, TRIP10
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 93%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

(1)H, (13)C and (15)N resonance assignments of the Cdc42-binding domain of TOCA1.
Watson et al. (2016)
2 more

5 mentions without citation

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.
Watson et al. (2016)
4 more