› 2je0

X-ray diffraction
2.4Å resolution

Crystal Structure of pp32

Released:
DOI: 10.2210/pdb2je0/pdb
PDB entry 2je0 coloured by chain, front view.
PDB entry 2je0 coloured by chain, side view.
PDB entry 2je0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the tumor suppressor protein pp32 (Anp32a): structural insights into Anp32 family of proteins.
Huyton T, Wolberger C
Protein Sci 16 1308-15 (2007)
PMID: 17567741

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153930 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acidic leucine-rich nuclear phosphoprotein 32 family member A Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 149 amino acids
Theoretical weight: 16.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P39687 (Residues: 1-149; Coverage: 60%)
Gene names: ANP32A, C15orf1, LANP, MAPM, PHAP1
Sequence domains: Leucine-rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
Ligand GOL 11 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2
Unit cell:
a: 106.501Å b: 183.237Å c: 67.477Å
α: 90° β: 104.39° γ: 90°
R-values:
R R work R free
0.221 0.218 0.269
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Host Cell Factors That Interact with Influenza Virus Ribonucleoproteins.
Staller et al. (2021)
23 other articles

7 mentions without citation

The crystal structure of the tumor suppressor protein pp32 (Anp32a): structural insights into Anp32 family of proteins.
Huyton et al. (2007)
6 more