2jay

X-ray diffraction
1.99Å resolution

Proteasome beta subunit PrcB from Mycobacterium tuberculosis

Released:
Entry authors: Oberschall A, Strizhov N, Bartunik HD

Function and Biology Details

Reaction catalysed:
Cleavage of peptide bonds with very broad specificity.

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-161583 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome subunit beta Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 30.33 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WHT9 (Residues: 1-291; Coverage: 100%)
Gene names: Rv2110c, prcB
Sequence domains: Proteasome subunit
Structure domains: Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P21
Unit cell:
a: 40.504Å b: 40.473Å c: 59.937Å
α: 90° β: 97.71° γ: 90°
R-values:
R R work R free
0.212 0.209 0.268
Expression system: Escherichia coli