2iv9

X-ray diffraction
1.9Å resolution

B2-appendage from AP2 in complex with Eps15 peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-154664 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 238 amino acids
Theoretical weight: 26.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P63010 (Residues: 700-937; Coverage: 25%)
Gene names: ADTB2, AP2B1, CLAPB1
Sequence domains:
Structure domains:
Epidermal growth factor receptor substrate 15 Chain: P
Molecule details ›
Chain: P
Length: 12 amino acids
Theoretical weight: 1.26 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P42566 (Residues: 719-730; Coverage: 1%)
Gene names: AF1P, EPS15

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 58.498Å b: 72.18Å c: 116.431Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.267
Expression systems:
  • Escherichia coli BL21
  • Not provided