› 2igf

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS

Released:
DOI: 10.2210/pdb2igf/pdb
PDB entry 2igf coloured by chain, front view.
PDB entry 2igf coloured by chain, side view.
PDB entry 2igf coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Stanfield RL, Fieser TM, Lerner RA, Wilson IA
Science 248 712-9 (1990)
PMID: 2333521

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
hetero trimer (preferred)
hetero hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-208761 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
IGG1-KAPPA B13I2 FAB (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.15 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
IGG1-KAPPA B13I2 FAB (HEAVY CHAIN) Chain: H
Molecule details ›
Chain: H
Length: 221 amino acids
Theoretical weight: 23.81 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
Myohemerythrin Chain: P
Molecule details ›
Chain: P
Length: 19 amino acids
Theoretical weight: 2.21 KDa
Source organism: Themiste hennahi
Expression system: Not provided
UniProt:
  • Canonical: P02247 (Residues: 69-87; Coverage: 16%)

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6322
Unit cell:
a: 142.5Å b: 142.5Å c: 101.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.22 not available
Expression system: Not provided

Quick links

Citations

27 review citations

The impact of glycosylation on the biological function and structure of human immunoglobulins.
Arnold et al. (2007)
26 more

10 mentions without citation

Structural basis of West Nile virus neutralization by a therapeutic antibody.
Nybakken et al. (2005)
9 more