› 2i0u

X-ray diffraction
2.2Å resolution

Crystal structures of phospholipases A2 from Vipera nikolskii venom revealing Triton X-100 bound in hydrophobic channel

Released:
DOI: 10.2210/pdb2i0u/pdb
PDB entry 2i0u coloured by chain, front view.
PDB entry 2i0u coloured by chain, side view.
PDB entry 2i0u coloured by chain, top view.
Source organism: Vipera berus nikolskii
Entry authors: Gao W, Bi RC

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo hexamer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-173053 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basic phospholipase A2 chain HDP-1P Chains: A, E
Molecule details ›
Chains: A, E
Length: 122 amino acids
Theoretical weight: 13.83 KDa
Source organism: Vipera berus nikolskii
UniProt:
  • Canonical: Q1RP79 (Residues: 17-138; Coverage: 100%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

4 bound ligands:
Ligand CA 2 x CA
Ligand SO4 2 x SO4
Ligand TRT 2 x TRT
Ligand TFA 1 x TFA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: R32
Unit cell:
a: 76.284Å b: 76.284Å c: 304.395Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.209 0.236

Quick links