› 2ghf

Solution NMR

Solution structure of the complete zinc-finger region of human zinc-fingers and homeoboxes 1 (ZHX1)

Released:
DOI: 10.2210/pdb2ghf/pdb
PDB entry 2ghf coloured by chain, ensemble of 20 models, front view.
PDB entry 2ghf coloured by chain, ensemble of 20 models, side view.
PDB entry 2ghf coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Wienk H, Structural Proteomics in Europe (SPINE)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc fingers and homeoboxes protein 1 Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 12.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKY1 (Residues: 60-153; Coverage: 11%)
Gene name: ZHX1
Sequence domains: Zinc-fingers and homeoboxes C2H2 finger domain
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Sparky ASSIGNMENT - CYANA structure calculations; run1: use 70% most intense peaks for initial fold, run2: refine initial fold using all peaks - water refinement with CNS
Expression system: Escherichia coli

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