› 2g7z

X-ray diffraction
2.05Å resolution

Conserved DegV-like Protein of Unknown Function from Streptococcus pyogenes M1 GAS Binds Long-chain Fatty Acids

Released:
DOI: 10.2210/pdb2g7z/pdb
PDB entry 2g7z coloured by chain, front view.
PDB entry 2g7z coloured by chain, side view.
PDB entry 2g7z coloured by chain, top view.
Source organism: Streptococcus pyogenes M1 GAS
Entry authors: Nocek B, Volkart L, Clancy S, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-159206 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DegV domain-containing protein SPy_1493/M5005_Spy1226 Chains: A, B
Molecule details ›
Chains: A, B
Length: 282 amino acids
Theoretical weight: 30.59 KDa
Source organism: Streptococcus pyogenes M1 GAS
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P67372 (Residues: 1-279; Coverage: 100%)
Gene names: M5005_Spy1226, SPy_1493
Sequence domains: Uncharacterised protein, DegV family COG1307
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand ZN 16 x ZN
Ligand CL 1 x CL
Ligand HXA 2 x HXA
Ligand TRS 2 x TRS
Ligand GOL 3 x GOL
1 modified residue:
Ligand MSE 14 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 74.126Å b: 74.093Å c: 128.597Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.165 0.207
Expression system: Escherichia coli BL21(DE3)

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