› 2fmd

X-ray diffraction
1.9Å resolution

Structural basis of carbohydrate recognition by Bowringia milbraedii seed agglutinin

Released:
DOI: 10.2210/pdb2fmd/pdb
PDB entry 2fmd coloured by chain, front view.
PDB entry 2fmd coloured by chain, side view.
PDB entry 2fmd coloured by chain, top view.
Source organism: Leucomphalos mildbraedii
Primary publication:
Structural basis of carbohydrate recognition by a Man(alpha1-2)Man-specific lectin from Bowringia milbraedii.
Buts L, Garcia-Pino A, Wyns L, Loris R
Glycobiology 16 635-40 (2006)
PMID: 16567368

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154493 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lectin Chain: A
Molecule details ›
Chain: A
Length: 240 amino acids
Theoretical weight: 25.58 KDa
Source organism: Leucomphalos mildbraedii
UniProt:
  • Canonical: P42088 (Residues: 1-240; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
2 bound ligands:
Ligand CA 1 x CA
Ligand MN 1 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: I222
Unit cell:
a: 66.603Å b: 86.351Å c: 91.76Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.183 0.228

Quick links

Citations

2 review citations

Mannose-Specific Lectins from Marine Algae: Diverse Structural Scaffolds Associated to Common Virucidal and Anti-Cancer Properties.
Barre et al. (2019)
1 more

2 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
1 more