› 2e8m

Solution NMR

Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8

Released:
DOI: 10.2210/pdb2e8m/pdb
PDB entry 2e8m coloured by chain, ensemble of 20 models, front view.
PDB entry 2e8m coloured by chain, ensemble of 20 models, side view.
PDB entry 2e8m coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Goroncy AK, Sato M, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171442 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor kinase substrate 8 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q12929 (Residues: 699-784; Coverage: 11%)
Gene name: EPS8
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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