Function and Biology Details
Reactions catalysed:
ATP + D-ribose 5-phosphate = diphosphate + ADP-D-ribose
ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate
8-oxo-GDP + H(2)O = 8-oxo-GMP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
ADP-sugar pyrophosphatase (preferred)
PDBe Complex ID:
PDB-CPX-193850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-sugar pyrophosphatase
Molecule details ›
Chains: A, B, C, D
Length: 227 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase
Length: 227 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9UKK9 (Residues: 1-219; Coverage: 100%)
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
BSRF BEAMLINE 3W1A
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
