› 2dg2

X-ray diffraction
2.45Å resolution

Crystal Structure of Mouse Apolipoprotein A-I Binding Protein

Released:
DOI: 10.2210/pdb2dg2/pdb
PDB entry 2dg2 coloured by chain, front view.
PDB entry 2dg2 coloured by chain, side view.
PDB entry 2dg2 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation.
Jha KN, Shumilin IA, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC
Endocrinology 149 2108-20 (2008)
PMID: 18202122

Function and Biology Details

Reaction catalysed: 
(6R)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide = (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185092 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD(P)H-hydrate epimerase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 265 amino acids
Theoretical weight: 29.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8K4Z3 (Residues: 25-282; Coverage: 92%)
Gene names: Aibp, Apoa1bp, Naxe
Sequence domains: YjeF-related protein N-terminus
Structure domains: YjeF N-terminal domain

Ligands and Environments

2 bound ligands:
Ligand SO4 6 x SO4
Ligand CL 6 x CL
1 modified residue:
Ligand MSE 42 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C2
Unit cell:
a: 104.855Å b: 125.745Å c: 163.62Å
α: 90° β: 106.56° γ: 90°
R-values:
R R work R free
0.207 0.206 0.228
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Phenotyping male infertility in the mouse: how to get the most out of a 'non-performer'.
Borg et al. (2010)
2 more

1 mention without citation

Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation.
Jha et al. (2008)