Function and Biology Details
Reaction catalysed:
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Formyl transferase, C-terminal domain superfamily
- Formyl transferase-like, C-terminal domain superfamily
- Formyl transferase, C-terminal
- Phosphoribosylglycinamide formyltransferase, active site
- Formyl transferase, N-terminal domain superfamily
- Formyl transferase, N-terminal
- Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Structure domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 36.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 329 amino acids
Theoretical weight: 36.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
O75891 (Residues: 1-307; Coverage: 34%)
Sequence domains:
Structure domains:
