› 2bkd

Solution NMR

Structure of the N-terminal domain of Fragile X Mental Retardation Protein

Released:
DOI: 10.2210/pdb2bkd/pdb
PDB entry 2bkd coloured by chain, ensemble of 20 models, front view.
PDB entry 2bkd coloured by chain, ensemble of 20 models, side view.
PDB entry 2bkd coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Ramos A, Hollingworth D, Adinolfi S, Castets M, Kelly G, Frenkiel TA, Bardoni B, Pastore A
Structure 14 21-31 (2006)
PMID: 16407062

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170388 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fragile X messenger ribonucleoprotein 1 Chain: N
Molecule details ›
Chain: N
Length: 134 amino acids
Theoretical weight: 15.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q06787 (Residues: 1-134; Coverage: 21%)
Gene name: FMR1
Sequence domains:
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RMD
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

17 review citations

Deciphering arginine methylation: Tudor tells the tale.
Chen et al. (2011)
16 more

5 mentions without citation

Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins.
Chen et al. (2015)
4 more