2bap

X-ray diffraction
3.3Å resolution

Crystal structure of the N-terminal mDia1 Armadillo Repeat Region and Dimerisation Domain in complex with the mDia1 autoregulatory domain (DAD)

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-126686 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein diaphanous homolog 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 36.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O08808 (Residues: 135-451; Coverage: 25%)
Gene names: Diap1, Diaph1
Sequence domains:
Structure domains:
Protein diaphanous homolog 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 56 amino acids
Theoretical weight: 6.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O08808 (Residues: 1145-1200; Coverage: 5%)
Gene names: Diap1, Diaph1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6122
Unit cell:
a: 138.45Å b: 138.45Å c: 210.89Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.292 0.288 0.364
Expression system: Escherichia coli BL21(DE3)