› 2a2g

X-ray diffraction
2.9Å resolution

THE CRYSTAL STRUCTURES OF A2U-GLOBULIN AND ITS COMPLEX WITH A HYALINE DROPLET INDUCER.

Released:
DOI: 10.2210/pdb2a2g/pdb
PDB entry 2a2g coloured by chain, front view.
PDB entry 2a2g coloured by chain, side view.
PDB entry 2a2g coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
The structures of alpha 2u-globulin and its complex with a hyaline droplet inducer.
Chaudhuri BN, Kleywegt GJ, Björkman J, Lehman-McKeeman LD, Oliver JD, Jones TA
Acta Crystallogr D Biol Crystallogr 55 753-62 (1999)
PMID: 10089305

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major urinary protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 181 amino acids
Theoretical weight: 20.76 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P02761 (Residues: 1-181; Coverage: 100%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand LEO 4 x LEO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 62.81Å b: 98.01Å c: 123.37Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.248 0.26

Quick links

Citations

6 review citations

Pathophysiology of chaperone-mediated autophagy.
Massey et al. (2004)
5 more

9 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
8 more