› 1ff3

X-ray diffraction
1.9Å resolution

STRUCTURE OF THE PEPTIDE METHIONINE SULFOXIDE REDUCTASE FROM ESCHERICHIA COLI

Released:
DOI: 10.2210/pdb1ff3/pdb
PDB entry 1ff3 coloured by chain, front view.
PDB entry 1ff3 coloured by chain, side view.
PDB entry 1ff3 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of the Escherichia coli peptide methionine sulphoxide reductase at 1.9 A resolution.
Tête-Favier F, Cobessi D, Boschi-Muller S, Azza S, Branlant G, Aubry A
Structure 8 1167-78 (2000)
PMID: 11080639

Function and Biology Details

Reaction catalysed: 
L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
homo tetramer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-141526 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide methionine sulfoxide reductase MsrA Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 211 amino acids
Theoretical weight: 23.31 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P0A744 (Residues: 2-212; Coverage: 100%)
Gene names: JW4178, b4219, msrA, pms
Sequence domains: Peptide methionine sulfoxide reductase
Structure domains: Peptide methionine sulphoxide reductase MsrA

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
1 modified residue:
Ligand CAS 3 x CAS

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P6522
Unit cell:
a: 102.5Å b: 102.5Å c: 292.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 0.218

Quick links

Citations

7 review citations

Arsenic binding to proteins.
Shen et al. (2013)
6 more

7 mentions without citation

Structure of Mycobacterium tuberculosis methionine sulfoxide reductase A in complex with protein-bound methionine.
Taylor et al. (2003)
6 more