› 1z1w

X-ray diffraction
2.7Å resolution

Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations

Released:
DOI: 10.2210/pdb1z1w/pdb
PDB entry 1z1w coloured by chain, front view.
PDB entry 1z1w coloured by chain, side view.
PDB entry 1z1w coloured by chain, top view.
Source organism: Thermoplasma acidophilum
Primary publication:
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations.
Kyrieleis OJ, Goettig P, Kiefersauer R, Huber R, Brandstetter H
J Mol Biol 349 787-800 (2005)
PMID: 15893768

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131678 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tricorn protease-interacting factor F3 Chain: A
Molecule details ›
Chain: A
Length: 780 amino acids
Theoretical weight: 89.49 KDa
Source organism: Thermoplasma acidophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: O93655 (Residues: 1-780; Coverage: 100%)
Gene names: Ta0815, trf3
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P3221
Unit cell:
a: 104.786Å b: 104.786Å c: 137.348Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.223 0.295
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Architecture and function of metallopeptidase catalytic domains.
Cerdà-Costa et al. (2014)
2 more

9 mentions without citation

Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families.
Pascual Alonso et al. (2023)
8 more