› 1yu3

X-ray diffraction
2.52Å resolution

Major Tropism Determinant I1 Variant

Released:
DOI: 10.2210/pdb1yu3/pdb
PDB entry 1yu3 coloured by chain, front view.
PDB entry 1yu3 coloured by chain, side view.
PDB entry 1yu3 coloured by chain, top view.
Source organism: Bordetella phage BIP-1
Primary publication:
The C-type lectin fold as an evolutionary solution for massive sequence variation.
McMahon SA, Miller JL, Lawton JA, Kerkow DE, Hodes A, Marti-Renom MA, Doulatov S, Narayanan E, Sali A, Miller JF, Ghosh P
Nat Struct Mol Biol 12 886-92 (2005)
PMID: 16170324

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181202 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tail fiber receptor-binding protein Chain: A
Molecule details ›
Chain: A
Length: 381 amino acids
Theoretical weight: 39.59 KDa
Source organism: Bordetella phage BIP-1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q775D6 (Residues: 1-381; Coverage: 100%)
Gene name: mtd
Sequence domains: Major tropism determinant N-terminal domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P63
Unit cell:
a: 92.308Å b: 92.308Å c: 102.29Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.17 0.213
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System.
Van Belleghem et al. (2018)
15 more

1 mention without citation

Insight into the Mechanism of Intramolecular Inhibition of the Catalytic Activity of Sirtuin 2 (SIRT2).
Li et al. (2015)