1ynl

X-ray diffraction
1.7Å resolution

Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeterners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-106912 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.12 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: A2P1G9 (Residues: 1-219; Coverage: 100%)
Gene names: Igk-C, Igkc
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.37 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q6PJB2 (Residues: 20-237; Coverage: 49%)
Gene name: Igh
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 136.226Å b: 48.14Å c: 76.09Å
α: 90° β: 109.53° γ: 90°
R-values:
R R work R free
0.208 0.207 0.241
Expression system: Not provided