› 1xvj

X-ray diffraction
1.8Å resolution

Crystal Structure Of Rat alpha-Parvalbumin D94S/G98E Mutant

Released:
DOI: 10.2210/pdb1xvj/pdb
PDB entry 1xvj coloured by chain, front view.
PDB entry 1xvj coloured by chain, side view.
PDB entry 1xvj coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of the D94S/G98E variant of rat alpha-parvalbumin. An explanation for the reduced divalent ion affinity.
Tanner JJ, Agah S, Lee YH, Henzl MT
Biochemistry 44 10966-76 (2005)
PMID: 16101280

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135967 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parvalbumin alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 109 amino acids
Theoretical weight: 11.86 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P02625 (Residues: 2-110; Coverage: 99%)
Gene names: Pva, Pvalb
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 30.719Å b: 56.988Å c: 56.493Å
α: 90° β: 105.81° γ: 90°
R-values:
R R work R free
0.199 0.197 0.236
Expression system: Escherichia coli

Quick links

Citations

2 mentions without citation

Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target.
Kim et al. (2017)
1 more