› 1xrz

Solution NMR

NMR Structure of a Zinc Finger with Cyclohexanylalanine Substituted for the Central Aromatic Residue

Released:
DOI: 10.2210/pdb1xrz/pdb
PDB entry 1xrz coloured by chain, ensemble of 34 models, front view.
PDB entry 1xrz coloured by chain, ensemble of 34 models, side view.
PDB entry 1xrz coloured by chain, ensemble of 34 models, top view.
Source organism: Homo sapiens
Primary publication:
Solvation and the hidden thermodynamics of a zinc finger probed by nonstandard repair of a protein crevice.
Lachenmann MJ, Ladbury JE, Qian X, Huang K, Singh R, Weiss MA
Protein Sci 13 3115-26 (2004)
PMID: 15557258

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139898 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger Y-chromosomal protein Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.61 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08048 (Residues: 570-598; Coverage: 4%)
Gene name: ZFY
Sequence domains: C2H2-type zinc-finger domain

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
1 modified residue:
Ligand ALC 1 x ALC

Experiments and Validation Details

Entry percentile scores
Refinement method: Distance geometry/simulated annealing followed by restrained molecular dynamics
Expression system: Not provided

Quick links

Citations

9 citation in other articles

Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528.
Makabe et al. (2008)
8 more