Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139852 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein kinase Lyn
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 65 amino acids
Theoretical weight: 7.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P07948 (Residues: 60-123; Coverage: 13%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Tyrosine-protein kinase-interacting protein
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.4 KDa
Source organism: Saimiriine gammaherpesvirus 2
Expression system: Escherichia coli BL21
UniProt:
Length: 22 amino acids
Theoretical weight: 2.4 KDa
Source organism: Saimiriine gammaherpesvirus 2
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P22575 (Residues: 170-191; Coverage: 9%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
XPLOR
Expression system: Escherichia coli BL21
