› 1tr8

X-ray diffraction
2.27Å resolution

Crystal Structure of archaeal Nascent Polypeptide-associated Complex (aeNAC)

Released:
DOI: 10.2210/pdb1tr8/pdb
PDB entry 1tr8 coloured by chain, front view.
PDB entry 1tr8 coloured by chain, side view.
PDB entry 1tr8 coloured by chain, top view.
Source organism: Methanothermobacter marburgensis
Primary publication:
The crystal structure of archaeal nascent polypeptide-associated complex (NAC) reveals a unique fold and the presence of a ubiquitin-associated domain.
Spreter T, Pech M, Beatrix B
J Biol Chem 280 15849-54 (2005)
PMID: 15665334

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nascent polypeptide-associated complex protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 11.96 KDa
Source organism: Methanothermobacter marburgensis
Expression system: Escherichia coli
UniProt:
  • Canonical: P0C0K9 (Residues: 19-117; Coverage: 85%)
Gene names: MTBMA_c06300, nac
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P43212
Unit cell:
a: 90.89Å b: 90.89Å c: 49.476Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.24
Expression system: Escherichia coli

Quick links

Citations

7 review citations

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins.
Kramer et al. (2009)
6 more

3 mentions without citation

Chaperone Interactions at the Ribosome.
Deuerling et al. (2019)
2 more