› 1to4

X-ray diffraction
1.55Å resolution

Structure of the cytosolic Cu,Zn SOD from S. mansoni

Released:
DOI: 10.2210/pdb1to4/pdb
PDB entry 1to4 coloured by chain, front view.
PDB entry 1to4 coloured by chain, side view.
PDB entry 1to4 coloured by chain, top view.
Source organism: Schistosoma mansoni
Primary publication:
Structure of the cytosolic Cu,Zn superoxide dismutase from Schistosoma mansoni.
Cardoso RM, Silva CH, Ulian de Araújo AP, Tanaka T, Tanaka M, Garratt RC
Acta Crystallogr D Biol Crystallogr 60 1569-78 (2004)
PMID: 15333927

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169527 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 156 amino acids
Theoretical weight: 15.97 KDa
Source organism: Schistosoma mansoni
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q01137 (Residues: 1-153; Coverage: 100%)
Gene name: SOD
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:
Ligand CU 4 x CU
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P21
Unit cell:
a: 39.27Å b: 95.08Å c: 78.41Å
α: 90° β: 103.55° γ: 90°
R-values:
R R work R free
0.158 0.157 0.171
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

The structural biochemistry of the superoxide dismutases.
Perry et al. (2010)
1 more

4 mentions without citation

Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database.
Tung et al. (2007)
3 more