› 1sy9

Solution NMR

Structure of calmodulin complexed with a fragment of the olfactory CNG channel

Released:
DOI: 10.2210/pdb1sy9/pdb
PDB entry 1sy9 coloured by chain, ensemble of 20 models, front view.
PDB entry 1sy9 coloured by chain, ensemble of 20 models, side view.
PDB entry 1sy9 coloured by chain, ensemble of 20 models, top view.
Source organisms:
Primary publication:
Structure of calmodulin complexed with an olfactory CNG channel fragment and role of the central linker: residual dipolar couplings to evaluate calmodulin binding modes outside the kinase family.
Contessa GM, Orsale M, Melino S, Torre V, Paci M, Desideri A, Cicero DO
J Biomol NMR 31 185-99 (2005)
PMID: 15803393

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144047 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP33 (Residues: 2-149; Coverage: 99%)
Gene name: calm1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Cyclic nucleotide-gated channel alpha-2 Chain: B
Molecule details ›
Chain: B
Length: 26 amino acids
Theoretical weight: 3.27 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: Q03041 (Residues: 60-85; Coverage: 4%)
Gene names: CNCG2, CNGA2

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

3 review citations

Weak alignment NMR: a hawk-eyed view of biomolecular structure.
Bax et al. (2005)
2 more

10 mentions without citation

The NMDA receptor NR1 C1 region bound to calmodulin: structural insights into functional differences between homologous domains.
Ataman et al. (2007)
9 more