› 1spf

Solution NMR

THE NMR STRUCTURE OF THE PULMONARY SURFACTANT-ASSOCIATED POLYPEPTIDE SP-C IN AN APOLAR SOLVENT CONTAINS A VALYL-RICH ALPHA-HELIX

Released:
DOI: 10.2210/pdb1spf/pdb
PDB entry 1spf coloured by chain, ensemble of 20 models, front view.
PDB entry 1spf coloured by chain, ensemble of 20 models, side view.
PDB entry 1spf coloured by chain, ensemble of 20 models, top view.
Source organism: Sus scrofa
Primary publication:
The NMR structure of the pulmonary surfactant-associated polypeptide SP-C in an apolar solvent contains a valyl-rich alpha-helix.
Johansson J, Szyperski T, Curstedt T, Wüthrich K
Biochemistry 33 6015-23 (1994)
PMID: 8180229

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147481 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Surfactant protein C Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 3.71 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P15785 (Residues: 1-35; Coverage: 100%)
Gene names: SFTP2, SFTPC
Sequence domains: Surfactant protein C, N terminal propeptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

25 review citations

Function of surfactant proteins B and C.
Weaver et al. (2001)
24 more

14 mentions without citation

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.
Willander et al. (2012)
13 more