› 1qo8

X-ray diffraction
2.15Å resolution

The structure of the open conformation of a flavocytochrome c3 fumarate reductase

Released:
DOI: 10.2210/pdb1qo8/pdb
PDB entry 1qo8 coloured by chain, front view.
PDB entry 1qo8 coloured by chain, side view.
PDB entry 1qo8 coloured by chain, top view.
Source organism: Shewanella frigidimarina
Primary publication:
Open conformation of a flavocytochrome c3 fumarate reductase.
Bamford V, Dobbin PS, Richardson DJ, Hemmings AM
Nat Struct Biol 6 1104-7 (1999)
PMID: 10581549

Function and Biology Details

Reaction catalysed: 
Succinate + a quinone = fumarate + a quinol
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195576 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable fumarate reductase Ifc3 Chains: A, D
Molecule details ›
Chains: A, D
Length: 566 amino acids
Theoretical weight: 60.76 KDa
Source organism: Shewanella frigidimarina
UniProt:
  • Canonical: Q9Z4P0 (Residues: 23-588; Coverage: 100%)
Gene names: Sfri_2586, ifcA
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand HEM 8 x HEM

Cofactor: Ligand FAD 2 x FAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P212121
Unit cell:
a: 71.77Å b: 109.69Å c: 227.32Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.281

Quick links

Citations

12 review citations

Bacterial respiration: a flexible process for a changing environment.
Richardson DJ. (2000)
11 more

7 mentions without citation

3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme.
Huang et al. (2006)
6 more