› 1qgm

Solution NMR

THE SOLUTION STRUCTURE OF A 30 RESIDUE AMINO-TERMINAL DOMAIN OF THE CARP GRANULIN-1 PROTEIN.

Released:
DOI: 10.2210/pdb1qgm/pdb
PDB entry 1qgm coloured by chain, ensemble of 15 models, front view.
PDB entry 1qgm coloured by chain, ensemble of 15 models, side view.
PDB entry 1qgm coloured by chain, ensemble of 15 models, top view.
Source organism: Cyprinus carpio
Primary publication:
A 30-residue fragment of the carp granulin-1 protein folds into a stack of two beta-hairpins similar to that found in the native protein.
Vranken WF, Chen ZG, Xu P, James S, Bennett HP, Ni F
J Pept Res 53 590-7 (1999)
PMID: 10424355

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160468 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Granulin-1 Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.2 KDa
Source organism: Cyprinus carpio
Expression system: Not provided
UniProt:
  • Canonical: P81013 (Residues: 1-30; Coverage: 53%)
Sequence domains: Granulin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Not provided

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Citations

1 review citation

The lysosomal function of progranulin, a guardian against neurodegeneration.
Paushter et al. (2018)
11 other articles

1 mention without citation

Endogenous growth factor stimulation of hemocyte proliferation induces resistance to Schistosoma mansoni challenge in the snail host.
Pila et al. (2016)