Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Large T antigen and Importin subunit alpha-1 (preferred)
PDBe Complex ID:
PDB-CPX-136538 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Large T antigen
Molecule details ›
Chains: A, B
Length: 25 amino acids
Theoretical weight: 2.69 KDa
Source organism: Betapolyomavirus macacae
Expression system: Not provided
UniProt:
Length: 25 amino acids
Theoretical weight: 2.69 KDa
Source organism: Betapolyomavirus macacae
Expression system: Not provided
UniProt:
- Canonical:
P03070 (Residues: 110-134; Coverage: 4%)
Importin subunit alpha-1
Molecule details ›
Chain: C
Length: 466 amino acids
Theoretical weight: 50.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 466 amino acids
Theoretical weight: 50.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL7-1
Spacegroup:
P212121
Expression systems:
- Not provided
- Escherichia coli
