› 1pzw

X-ray diffraction
2Å resolution

Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone

Released:
DOI: 10.2210/pdb1pzw/pdb
PDB entry 1pzw coloured by chain, front view.
PDB entry 1pzw coloured by chain, side view.
PDB entry 1pzw coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module.
Jauch R, Bourenkov GP, Chung HR, Urlaub H, Reidt U, Jäckle H, Wahl MC
Structure 11 1393-402 (2003)
PMID: 14604529

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193606 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor grauzone Chain: A
Molecule details ›
Chain: A
Length: 80 amino acids
Theoretical weight: 9.17 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9U405 (Residues: 2-81; Coverage: 14%)
Gene names: CG3282, grau
Sequence domains: Zinc-finger associated domain (zf-AD)
Structure domains: His-Me finger endonuclease fold

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P41212
Unit cell:
a: 48.66Å b: 48.66Å c: 82.123Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.241 0.267
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Mechanisms and proteins involved in long-distance interactions.
Maksimenko et al. (2014)
2 more

3 mentions without citation

Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila.
Bonchuk et al. (2021)
2 more