› 1pmd

X-ray diffraction
3.5Å resolution

PENICILLIN-BINDING PROTEIN 2X (PBP-2X)

Released:
DOI: 10.2210/pdb1pmd/pdb
PDB entry 1pmd coloured by chain, front view.
PDB entry 1pmd coloured by chain, side view.
PDB entry 1pmd coloured by chain, top view.
Source organism: Streptococcus pneumoniae
Primary publication:
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
Pares S, Mouz N, Pétillot Y, Hakenbeck R, Dideberg O
Nat Struct Biol 3 284-9 (1996)
PMID: 8605631

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147020 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Penicillin-binding protein 2x Chain: A
Molecule details ›
Chain: A
Length: 675 amino acids
Theoretical weight: 73.92 KDa
Source organism: Streptococcus pneumoniae
UniProt:
  • Canonical: P14677 (Residues: 76-750; Coverage: 90%)
Gene names: SP_0336, pbpX
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6122
Unit cell:
a: 161.25Å b: 161.25Å c: 170.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.225 0.211

Quick links

Citations

21 review citations

The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis.
Sauvage et al. (2008)
20 more

3 mentions without citation

Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.
Ho et al. (2000)
2 more