› 1mwz

Solution NMR

Solution structure of the N-terminal domain of ZntA in the Zn(II)-form

Released:
DOI: 10.2210/pdb1mwz/pdb
PDB entry 1mwz coloured by chain, ensemble of 30 models, front view.
PDB entry 1mwz coloured by chain, ensemble of 30 models, side view.
PDB entry 1mwz coloured by chain, ensemble of 30 models, top view.
Source organism: Escherichia coli
Primary publication:
A new zinc-protein coordination site in intracellular metal trafficking: solution structure of the Apo and Zn(II) forms of ZntA(46-118).
Banci L, Bertini I, Ciofi-Baffoni S, Finney LA, Outten CE, O'Halloran TV
J Mol Biol 323 883-97 (2002)
PMID: 12417201

Function and Biology Details

Reactions catalysed: 
ATP + H(2)O + Zn(2+)(Side 1) = ADP + phosphate + Zn(2+)(Side 2)
ATP + H(2)O + Cd(2+)(Side 1) = ADP + phosphate + Cd(2+)(Side 2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc/cadmium/lead-transporting P-type ATPase Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 7.94 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P37617 (Residues: 46-118; Coverage: 10%)
Gene names: JW3434, b3469, yhhO, zntA
Sequence domains: Heavy-metal-associated domain
Structure domains: Alpha-Beta Plaits

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

19 review citations

Copper metallochaperones.
Robinson et al. (2010)
18 more

1 mention without citation

Structure and signaling mechanism of Per-ARNT-Sim domains.
Möglich et al. (2009)