› 1m9u

X-ray diffraction
2.3Å resolution

Crystal Structure of Earthworm Fibrinolytic Enzyme Component A from Eisenia fetida

Released:
DOI: 10.2210/pdb1m9u/pdb
PDB entry 1m9u coloured by chain, front view.
PDB entry 1m9u coloured by chain, side view.
PDB entry 1m9u coloured by chain, top view.
Source organism: Eisenia fetida
Primary publication:
Crystal structure of earthworm fibrinolytic enzyme component a: revealing the structural determinants of its dual fibrinolytic activity.
Tang Y, Liang D, Jiang T, Zhang J, Gui L, Chang W
J. Mol. Biol. 321 57-68 (2002)
PMID: 12139933

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidase S1 domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 241 amino acids
Theoretical weight: 24.66 KDa
Source organism: Eisenia fetida
UniProt:
  • Canonical: Q8MX72 (Residues: 1-241; Coverage: 100%)
Gene names: Efp-2, a1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CONVENTIONAL Cu
Spacegroup: P212121
Unit cell:
a: 40.6Å b: 126.1Å c: 129.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.236

Quick links

Citations

2 review citations

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.
Wong et al. (2014)
1 more

5 mentions without citation

Modeling and structural analysis of PA clan serine proteases.
Laskar et al. (2012)
4 more