Function and Biology Details
Reaction catalysed:
Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Pyruvate dehydrogenase E1 component (preferred)
PDBe Complex ID:
PDB-CPX-142723 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate dehydrogenase E1 component
Molecule details ›
Chains: A, B
Length: 886 amino acids
Theoretical weight: 99.66 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 886 amino acids
Theoretical weight: 99.66 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P0AFG8 (Residues: 2-887; Coverage: 100%)
Sequence domains:
- Transketolase, thiamine diphosphate binding domain
- Pyruvate dehydrogenase E1 component middle domain
