› 1l0z

X-ray diffraction
1.5Å resolution

THE STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH XENON AND BROMIDE, CRYOPROTECTED WITH DRY PARAFFIN OIL

Released:
DOI: 10.2210/pdb1l0z/pdb
PDB entry 1l0z coloured by chain, front view.
PDB entry 1l0z coloured by chain, side view.
PDB entry 1l0z coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Xenon derivatization of halide-soaked protein crystals.
Panjikar S, Tucker PA
Acta Crystallogr D Biol Crystallogr 58 1413-20 (2002)
PMID: 12198297

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133451 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chymotrypsin-like elastase family member 1 Chain: A
Molecule details ›
Chain: A
Length: 240 amino acids
Theoretical weight: 25.93 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00772 (Residues: 27-266; Coverage: 96%)
Gene names: CELA1, ELA1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand BR 32 x BR
Ligand XE 1 x XE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P212121
Unit cell:
a: 49.5Å b: 57.7Å c: 73.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.166 0.209

Quick links

Citations

3 citation in other articles

Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Ellisdon et al. (2015)
2 more

1 mention without citation

Chlamydia protein Pgp3 studied at high resolution in a new crystal form.
Khurshid et al. (2018)