› 1kt9

X-ray diffraction
1.98Å resolution

Crystal Structure of C. elegans Ap4A Hydrolase

Released:
DOI: 10.2210/pdb1kt9/pdb
PDB entry 1kt9 coloured by chain, front view.
PDB entry 1kt9 coloured by chain, side view.
PDB entry 1kt9 coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms.
Bailey S, Sedelnikova SE, Blackburn GM, Abdelghany HM, Baker PJ, McLennan AG, Rafferty JB
Structure 10 589-600 (2002)
PMID: 11937063

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193601 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.91 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9U2M7 (Residues: 1-138; Coverage: 100%)
Gene names: Y37H9A.6, ndx-4
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: C2221
Unit cell:
a: 62.794Å b: 72.934Å c: 61.046Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.213
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Structures and mechanisms of Nudix hydrolases.
Mildvan et al. (2005)
2 more

5 mentions without citation

The Prodigal Compound: Return of Ribosyl 1,5-Bisphosphate as an Important Player in Metabolism.
Hove-Jensen et al. (2019)
4 more