1kt2

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE

Released:
Source organisms:
Primary publication:
Structural basis of cytochrome c presentation by IE(k).
J Exp Med 195 1043-52 (2002)
PMID: 11956295

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-135360 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class II histocompatibility antigen, E-D alpha chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 182 amino acids
Theoretical weight: 21.2 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P01904 (Residues: 26-207; Coverage: 79%)
Gene name: H2-Ea
Sequence domains:
Structure domains:
H-2 class II histocompatibility antigen, E-B beta chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 213 amino acids
Theoretical weight: 24.4 KDa
Source organism: Lonomia obliqua
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P04230 (Residues: 30-215; Coverage: 78%)
Gene name: H2-Eb1
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 147.79Å b: 56.93Å c: 115.99Å
α: 90° β: 92.12° γ: 90°
R-values:
R R work R free
0.22 0.22 0.294
Expression system: Spodoptera frugiperda