Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139910 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin-like growth factor 1 receptor beta chain
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 34.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Length: 299 amino acids
Theoretical weight: 34.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P08069 (Residues: 988-1286; Coverage: 22%)
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Insulin receptor substrate 1
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.6 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 14 amino acids
Theoretical weight: 1.6 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P35568 (Residues: 889-902; Coverage: 1%)
