› 1gn6

X-ray diffraction
2.9Å resolution

G152A mutant of Mycobacterium tuberculosis iron-superoxide dismutase.

Released:
DOI: 10.2210/pdb1gn6/pdb
PDB entry 1gn6 coloured by chain, front view.
PDB entry 1gn6 coloured by chain, side view.
PDB entry 1gn6 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
X-ray structure analysis of an engineered Fe-superoxide dismutase Gly-Ala mutant with significantly reduced stability to denaturant.
Cooper JB, Saward S, Erskine PT, Badasso MO, Wood SP, Zhang Y, Young D
FEBS Lett. 387 105-8 (1996)
PMID: 8674528

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Fe] Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 207 amino acids
Theoretical weight: 23.07 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Mycolicibacterium vaccae
UniProt:
  • Canonical: P9WGE7 (Residues: 1-207; Coverage: 100%)
Gene names: MTCY01A6.22c, Rv3846, sod, sodA, sodB
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FE 4 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P21
Unit cell:
a: 68.7Å b: 85.6Å c: 66.7Å
α: 90° β: 99.8° γ: 90°
R-values:
R R work R free
0.169 0.169 not available
Expression system: Mycolicibacterium vaccae

Quick links

Citations

5 citation in other articles

Iron superoxide dismutase from the archaeon Sulfolobus solfataricus: analysis of structure and thermostability.
Ursby et al. (1999)
4 more

1 mention without citation

Dynamic Allostery of the Catabolite Activator Protein Revealed by Interatomic Forces.
Louet et al. (2015)