› 1ghu

Solution NMR

NMR solution structure of growth factor receptor-bound protein 2 (GRB2) SH2 domain, 24 structures

Released:
DOI: 10.2210/pdb1ghu/pdb
PDB entry 1ghu coloured by chain, ensemble of 24 models, front view.
PDB entry 1ghu coloured by chain, ensemble of 24 models, side view.
PDB entry 1ghu coloured by chain, ensemble of 24 models, top view.
Source organism: Homo sapiens
Primary publication:
Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain.
Thornton KH, Mueller WT, McConnell P, Zhu G, Saltiel AR, Thanabal V
Biochemistry 35 11852-64 (1996)
PMID: 8794768

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158852 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62993 (Residues: 60-161; Coverage: 47%)
Gene names: ASH, GRB2
Sequence domains: SH2 domain
Structure domains: SH2 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 citation in other articles

Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain.
Oligino et al. (1997)
13 more