Function and Biology Details
Reaction catalysed:
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Thioredoxin reductase complex and Thioredoxin 1 (preferred)
PDBe Complex ID:
PDB-CPX-141910 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thioredoxin reductase
Molecule details ›
Chains: A, B, E, F
Length: 320 amino acids
Theoretical weight: 34.51 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Pyridine nucleotide-disulphide oxidoreductase
Structure domains: FAD/NAD(P)-binding domain
Length: 320 amino acids
Theoretical weight: 34.51 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P0A9P4 (Residues: 2-321; Coverage: 100%)
Sequence domains: Pyridine nucleotide-disulphide oxidoreductase
Structure domains: FAD/NAD(P)-binding domain
Thioredoxin 1
Molecule details ›
Chains: C, D, G, H
Length: 108 amino acids
Theoretical weight: 11.67 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin
Length: 108 amino acids
Theoretical weight: 11.67 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0AA25 (Residues: 2-109; Coverage: 99%)
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin
