1eih

Solution NMR

SOLUTION STRUCTURE OF THE HUMAN CHEMOKINE EOTAXIN-2

Released:
Source organism: Homo sapiens
Primary publication:
NMR solution structure and receptor peptide binding of the CC chemokine eotaxin-2.
Biochemistry 39 8382-95 (2000)
PMID: 10913244

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126135 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 24 Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 8.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00175 (Residues: 27-99; Coverage: 79%)
Gene names: CCL24, MPIF2, SCYA24
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: hybrid distance geometry/simulated annealing
Expression system: Escherichia coli