› 1dps

X-ray diffraction
1.6Å resolution

THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA

Released:
DOI: 10.2210/pdb1dps/pdb
PDB entry 1dps coloured by chain, front view.
PDB entry 1dps coloured by chain, side view.
PDB entry 1dps coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
The crystal structure of Dps, a ferritin homolog that binds and protects DNA.
Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM
Nat Struct Biol 5 294-303 (1998)
PMID: 9546221

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142207 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA protection during starvation protein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 167 amino acids
Theoretical weight: 18.74 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABT2 (Residues: 1-167; Coverage: 100%)
Gene names: JW0797, b0812, dps, pexB, vtm
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:
Ligand NA 12 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21212
Unit cell:
a: 134.41Å b: 139.65Å c: 118.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.22
Expression system: Escherichia coli

Quick links

Citations

58 review citations

Bacterial iron homeostasis.
Andrews et al. (2003)
57 more

22 mentions without citation

Dps Is a Universally Conserved Dual-Action DNA-Binding and Ferritin Protein.
Orban et al. (2022)
21 more