› 1bus

Solution NMR

SOLUTION CONFORMATION OF PROTEINASE INHIBITOR IIA FROM BULL SEMINAL PLASMA BY 1H NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY

Released:
DOI: 10.2210/pdb1bus/pdb
PDB entry 1bus coloured by chain, ensemble of 5 models, front view.
PDB entry 1bus coloured by chain, ensemble of 5 models, side view.
PDB entry 1bus coloured by chain, ensemble of 5 models, top view.
Source organism: Bos taurus
Primary publication:
Solution conformation of proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry.
Williamson MP, Havel TF, Wüthrich K
J Mol Biol 182 295-315 (1985)
PMID: 3839023

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133772 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease inhibitor Kazal-type 6 Chain: A
Molecule details ›
Chain: A
Length: 57 amino acids
Theoretical weight: 6.19 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01001 (Residues: 24-80; Coverage: 100%)
Gene name: SPINK6
Sequence domains: Kazal-type serine protease inhibitor domain
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

49 review citations

Natural protein proteinase inhibitors and their interaction with proteinases.
Bode et al. (1992)
48 more

2 mentions without citation

A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase.
Brillard-Bourdet et al. (2006)
1 more