› 1bj5

X-ray diffraction
2.5Å resolution

HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID

Released:
DOI: 10.2210/pdb1bj5/pdb
PDB entry 1bj5 coloured by chain, front view.
PDB entry 1bj5 coloured by chain, side view.
PDB entry 1bj5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.
Curry S, Mandelkow H, Brick P, Franks N
Nat Struct Biol 5 827-35 (1998)
PMID: 9731778

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 585 amino acids
Theoretical weight: 66.57 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

1 bound ligand:
Ligand MYR 5 x MYR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: C2
Unit cell:
a: 189.18Å b: 38.96Å c: 96.4Å
α: 90° β: 105.31° γ: 90°
R-values:
R R work R free
0.224 0.224 0.279
Expression system: Saccharomyces cerevisiae

Quick links

Citations

75 review citations

Neuroprotection for ischemic stroke: past, present and future.
Ginsberg MD. (2008)
74 more

33 mentions without citation

How α-Helical Motifs Form Functionally Diverse Lipid-Binding Compartments.
Malinina et al. (2017)
32 more