› 1b7b

X-ray diffraction
2.8Å resolution

Carbamate kinase from Enterococcus faecalis

Released:
DOI: 10.2210/pdb1b7b/pdb
PDB entry 1b7b coloured by chain, front view.
PDB entry 1b7b coloured by chain, side view.
PDB entry 1b7b coloured by chain, top view.
Source organism: Enterococcus faecium
Primary publication:
Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine.
Marina A, Alzari PM, Bravo J, Uriarte M, Barcelona B, Fita I, Rubio V
Protein Sci 8 934-40 (1999)
PMID: 10211841

Function and Biology Details

Reaction catalysed: 
(1a) ATP + carbamate = ADP + carbamoyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbamate kinase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 310 amino acids
Theoretical weight: 32.96 KDa
Source organism: Enterococcus faecium
UniProt:
  • Canonical: P0A2X8 (Residues: 1-310; Coverage: 100%)
Gene names: arcC, arcC-1, arcC1
Sequence domains: Amino acid kinase family
Structure domains: Acetylglutamate kinase-like

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P212121
Unit cell:
a: 80.86Å b: 172.92Å c: 98.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.283

Quick links

Citations

3 review citations

An ecological and evolutionary context for integrated nitrogen metabolism and related signaling pathways in marine diatoms.
Allen et al. (2006)
2 more

4 mentions without citation

A comprehensive update of the sequence and structure classification of kinases.
Cheek et al. (2005)
3 more